Figure 2
From: Altered epithelial barrier functions in the colon of patients with spina bifida
(A) and (B) Comparison of para- and transcellular permeability in patients with Spina Bifida and healthy volunteers (Hvs). (A) The paracellular permeability was significantly increased in patients with SB (p = 0008). (B) For the evaluation of transcellular permeability, no significant changes were observed between the two groups (p = 0.16). (C,D) The expression levels of claudin 1 and ZO1 assessed in Western Blot were comparable between the two groups. (D) The average claudin 1 area/crypt tended to be lower in patients with SB (p = 0.08). (E) The average ZO1 area /crypt were comparable between the two groups.
