Table 4 The effects of heavy metal burden on BMI, blood parameters, biochemical profile, and reproductive hormones concentration of brick kiln male workers and controls.
Blood parameters | Control | Exposed | P value statistics |
|---|---|---|---|
Average BMI (Kg/m2) | 26.9 ± 0.77 | 23.0 ± 0.23*** | P = 0.000 |
WBC (1 × 103) | 8.17 ± 0.40 | 8.84 ± 0.25 | P = 0.163 |
HGB (g/dL) | 14.1 ± 0.26 | 12.5 ± 0.41*** | P = 0.001 |
RBC (1 × 103) | 5081.8 ± 63.7 | 4295.4 ± 89.2*** | P = 0.000 |
HCT (%) | 43.7 ± 0.84 | 38.7 ± 1.12*** | P = 0.001 |
MCV (fL) | 87.5 ± 0.92 | 82.5 ± 1.52** | P = 0.007 |
MCH (pg) | 28.4 ± 0.36 | 26.5 ± 0.63* | P = 0.012 |
MCHC (g/dL) | 32.5 ± 0.18 | 32.0 ± 0.25* | P = 0.088 |
RDW-CV (%) | 13.6 ± 0.17 | 15.8 ± 0.49*** | P = 0.001 |
RWD-SD (fL) | 42.2 ± 0.46 | 46.3 ± 0.95*** | P = 0.001 |
PLT (1 × 103) | 246.9 ± 11.6 | 293.1 ± 12.95** | P = 0.010 |
MPV (fL) | 8.99 ± 0.12 | 9.02 ± 0.12 | P = 0.898 |
PDW (%) | 15.4 ± 0.04 | 15.5 ± 0.03 | P = 0.194 |
PCT (%) | 0.22 ± 0.01 | 0.260 ± 0.01* | P = 0.029 |
Oxidants/antioxidants concentrations | |||
SOD (U/min) | 16.9 ± 0.72 | 14.4 ± 0.49** | P = 0.006 |
POD (nmole) | 21.7 ± 2.22 | 19.2 ± 1.44 | P = 0.393 |
ROS (μmol/min) | 1.17 ± 0.06 | 1.50 ± 0.07*** | P = 0.001 |
MDA (nmol /ml) | 4.69 ± 0.36 | 5.28 ± 0.40* | P = 0.279 |
Protein estimation (g/dl) | 11.6 | 8.95* | P = 0.013 |
Reproductive hormones levels | |||
FSH (mIU/ml) | 12.19 ± 0.21 | 17.9 ± 0.44*** | P = 0.000 |
LH (mIU/ml) | 7.86 ± 0.12 | 10.8 ± 0.19*** | P = 0.000 |
Testosterone (ng/ml) | 5.80 ± 0.06 | 2.13 ± 0.12*** | P = 0.000 |
Cortisol (µg/dl) | 18.3 ± 0.41 | 30.4 ± 0.52*** | P = 0.000 |
