Table 2 Univariate and multiple logistic regression analyses of factors associated with remarkable response to nalfurafine hydrochloride.

From: Shorter pruritus period and milder disease stage are associated with response to nalfurafine hydrochloride in patients with chronic liver disease

Factor

Univariate analysis

Multivariate analysis

OR

95%CI

P value

OR

95%CI

P value

Age

0.99

0.97–1.01

0.44

   

Body weight

0.99

0.98–1.02

0.96

   

Itching period

0.96

0.93–0.99

2.70 × 10–3

0.96

0.92–0.99

2.10 × 10–3

Baseline VAS

1.01

0.99–1.03

0.24

   

Child–Pugh class C (vs. A and B)

0.46

0.24–0.89

2.17 × 10–2

   

Hepatocellular carcinoma (presence)

1.50

0.85–2.63

0.16

   

Platelet

1.05

1.03–1.09

2.28 × 10–4

   

PT

1.02

1.00–1.03

5.58 × 10–4

   

AST

1.00

0.99–1.00

0.23

   

ALT

1.00

0.99–1.00

0.99

   

Total bilirubin

0.97

0.91–1.05

0.48

   

ALP

1.00

0.99–1.00

0.66

   

Creatinine

1.10

0.95–1.28

0.19

   

FIB-4 index

0.84

0.77–0.91

8.07 × 10–6

0.83

0.81–0.99

2.08 × 10–3

ALBI score

0.57

0.43–0.77

2.02 × 10–4

   
  1. OR odds ratio, CI confidence interval, VAS Visual Analog Scale, AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, FIB-4 fibrosis-4.
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