Table 3 Univariate and multiple logistic regression analyses of factors associated with relevant response to nalfurafine hydrochloride.

From: Shorter pruritus period and milder disease stage are associated with response to nalfurafine hydrochloride in patients with chronic liver disease

Factor

Univariate analysis

Multivariate analysis

OR

95%CI

P value

OR

95%CI

P value

Age

1.00

0.98–1.02

0.44

   

Body weight

1.01

0.99–1.03

0.96

   

Itching period

0.97

0.96–0.99

1.15 × 10–2

0.95

0.93–0.98

2.95 × 10–3

Baseline VAS

1.01

0.99–1.03

0.46

   

Child–Pugh Class C (vs. A and B)

0.40

0.22–0.74

3.47 × 10–2

   

Hepatocellular carcinoma (presence)

1.36

0.73–2.54

0.34

   

Platelet

1.01

0.98–1.04

0.37

   

PT

1.00

0.99–1.01

0.73

   

AST

0.99

0.98–1.00

0.07

   

ALT

1.00

0.99–1.00

0.26

   

Total bilirubin

0.91

0.85–0.99

2.25 × 10–2

   

Creatinine

1.06

0.91–1.23

0.46

   

FIB-4 index

0.95

0.90–1.01

0.09

   

ALBI score

0.78

0.59–1.05

0.10

   
  1. OR odds ratio, CI confidence interval, VAS Visual Analog Scale, AST aspartate aminotransferase, ALT alanine aminotransferase, FIB-4 fibrosis-4.
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