Table 1 Experimental parameters for the evaluation of C-ions triggered PVA/PFB NDs vaporization at 37 °C and 312/u MeV beam energy.

From: Ultrasound-assisted carbon ion dosimetry and range measurement using injectable polymer-shelled phase-change nanodroplets: in vitro study

Experiment

Dose (Gy)

Fluence (C-ions/cm2)

NDs concentration (× 106 ND/ml)

Dose rate (%)

Beam range (mm)

Phantom entrance position (mm)

Number of irradiated phantoms

Dose effect

0.1–4

1.25 × 106 − 5 × 107

4

100

180

144

8

Concentration effect

1

1.25 × 107

0.8–8

100

180

144

8

Dose rate effect

1

1.25 × 107

4

50

180

144

2

Specificity and range verification

Phantom shift

4

5 × 107

8

100

180

154

2

SOBP

1

1.25 × 107

4

100

180

144

2

Range change

1

1.25 × 107

4

100

50

20

2

  1. The values highlighted in bold are considered to be the reference parameters for the different tests.
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