Figure 2 | Scientific Reports

Figure 2

From: Differential expression analysis of genes and long non-coding RNAs associated with KRAS mutation in colorectal cancer cells

Figure 2

Heatmap plots based on the DEGs showing clustering of mtKRAS and wtKRAS cells lines into two distinct groups based on DEGs. (a) Clustering of HCT-116 and SW48 samples. (b) Clustering of LoVo and SW48 samples. Red shows overexpression and blue indicates underexpression with absolute log2FC > 1.5 and adjusted p-value < 0.05. Expression data are represented as normalized values (Z‑scores). Heatmap plot was created using gplots package in R environment and variance stabilizing transformation (VST) was applied to the normalized count data from DESeq2 package.

Back to article page