Table 2 List of TFs regulating the identified DEGs using Enrichr Tool through scanning the TRANSFAC and JASPAR databases.
Symbol | Description | Feature |
|---|---|---|
TFAP2A | Transcription factor AP-2, alpha | Reduced expression in CRC progression |
SP1 | Specificity protein 1 | High expression related to poor prognosis of CRC |
ZBTB7A | Zinc finger and BTB domain-containing 7A | As an oncogene in CRC |
HNRNPK | Heterogeneous nuclear ribonucleoprotein K | Overexpression with poor prognosis in CRC |
EGR1 | Early growth response-1 | CRC cell proliferation |
TEAD4 | TEA domain family member 4 | Promotion of CRC tumorigenesis |
HOXD9 | Homeobox Protein Hox-D9 | Promotion of metastasis in CRC |
SP3 | Specificity protein 3 | Induction of EMT of CRC |
PCBP1 | Poly(RC) Binding Protein 1 | Induction of drug resistant CRC |
MTF1 | Metal Regulatory Transcription Factor 1 | Association with EMT in CRC |
UBTF | Upstream Binding Transcription Factor | Promotion of CRC cell proliferation |
