Figure 3
Comparison of expression changes in observed Raf926 mutants with key germ layer marker genes. (A) Expression profiles of key germ layer marker genes in WT and Raf926 mutant embryos. (B) Raf926 mutants show upregulation of ectoderm marker genes, along with downregulation of neuroectoderm and mesoderm marker genes. (C) Upset plot showing the overlap between differentially expressed genes in Raf926 mutant with clusters of gene expression changes observed after generating embryos with only one germ layer after perturbing the Toll pathway (see S. Fig. 3D).
