Table 2 A comparative analysis of the different immunological parameters of the patients measured at the time of admission, differentiating Group 1 (N = 26) from Group 2 (N = 25) and Group 3 (N = 25).

From: A comparative analysis depicting the disease characteristics and phylogenetic signature of human cytomegalovirus infection in Human Immunodeficiency Virus 1 seropositive patients with end-organ retinitis and gastro-enteric diseases

Parameters

Groups

Mean ± SD

Significance

95% CI

TGFβ (pg/mL)

Group 1

250.32 + 55.9

Constant

Constant

Group 2

187.98 + 16.15

0.001

21.96 to 102.73

Group 3

121.83 + 15.79

0.001

88.11 to 168.87

IL10 (pg/mL)

Group 1

27.12 + 4.95

Constant

Constant

Group 2

29.03 + 5.98

1.00

− 7.59 to 3.77

Group 3

35.86 + 7.3

0.001

− 14.43 to − 3.05

IL7 (pg/mL)

Group 1

180.12 ± 23.54

Constant

Constant

Group 2

190.9 ± 10.38

0.62

− 31.73 to 10.17

Group 3

184.5 ± 25.22

1.00

− 25.36 to 16.54

IFNγ (pg/mL)

Group 1

23.57 ± 6.83

Constant

Constant

Group 2

17.84 ± 2.25

0.04

0.204 to 11.26

Group 3

14.5 ± 5.42

0.001

3.54 to 14.59

TNFα (pg/mL)

Group 1

127.25 + 26.13

Constant

Constant

Group 2

96.21 ± 7.92

0.001

11.602 to 50.48

Group 3

40.79 ± 11.92

0.002

67.02 to 105.9

IL6 (pg/mL)

Group 1

32.6 ± 8.04

Constant

Constant

Group 2

37.6 ± 7.17

0.272

− 12.81 to 2.32

Group 3

30.05 ± 7.84

1.000

− 5.2 to 9.92

IL1β (pg/mL)

Group 1

123.98 + 38.72

Constant

Constant

Group 2

91.64 + 7.3

0.016

4.86 to 59.87

Group 3

45.72 + 9.07

0.001

50.75 to 105.7

CRP (mg/L)

Group 1

19.04 + 2.69

Constant

Constant

Group 2

18.09 + 2.4

1.00

− 1.64 to 3.55

Group 3

7.96 + 2.25

0.001

8.48 to 13.68

MCP1 (pg/mL)

Group 1

611.33 + 56.1

Constant

Constant

Group 2

603.28 + 41.23

1.00

− 45.46 to 61.56

Group 3

472.55 + 64.23

0.001

85.25 to 192.28

MIP1α (pg/mL)

Group 1

39.05 + 9.49

Constant

Constant

Group 2

37.64 ± 12.73

1.00

− 8.25 to 11.07

Group 3

37.11 ± 7.37

1.00

− 7.72 to 11.6

CXCL10 (pg/mL)

Group 1

884.3 ± 58.8

Constant

Constant

Group 2

569.9 ± 55.7

0.001

263.7 to 364.8

Group 3

403.15 ± 26.6

0.001

430.6 to 531.6

  1. Mean ± SD values were calculated and one way ANOVA was performed using Bonferroni method (Post-hoc analysis) for comparing the mean values of each group with respect to that of Group 1.