Table 3 Binary logistic regression analysis of the selected significant heamatological and immunological factors to ascertain their role while significantly comparing between HCMV induced Retinitis (HR; N = 15) and HCMV induced Gastroenteric disease (HG; N = 11) cases among HIV infected Group 1 patients.

From: A comparative analysis depicting the disease characteristics and phylogenetic signature of human cytomegalovirus infection in Human Immunodeficiency Virus 1 seropositive patients with end-organ retinitis and gastro-enteric diseases

Parameters

Mean ± SD

Significance

Beta coefficient

95% CI

Lower

Upper

CD4+ T-cell count

HR

52.3 ± 16.4

0.052

1.069

1.00

1.143

HG

72 ± 19.48

Neutrophil

HR

0.51 ± 0.22

0.746

0.535

0.012

23.406

HG

0.48 ± 0.27

Hematocrit

HR

17.95 ± 4.17

0.465

1.102

0.85

1.43

HG

19.1 ± 2.95

HCMV viral load

HR

92.98 ± 44.5

0.035

1.025

0.998

1.053

HG

140.7 ± 48.8

TGFβ (Pg/mL)

HR

288.65 ± 35.31

0.016

0.957

0.924

0.992

HG

212 ± 45.66

TNFα (Pg/mL)

HR

102.96 ± 7.63

0.033

1.652

0.886

1.642

HG

151.55 ± 8.47

IL1β (Pg/mL)

HR

95.43 ± 11.46

0.022

1.207

0.987

1.475

HG

152.53 ± 34.9

CXCL10 (Pg/mL)

HR

922.53 ± 47.9

0.02

0.963

0.933

0.994

HG

844.02 ± 41.96

IFNγ (Pg/mL)

HR

25.28 ± 7.41

0.266

0.921

0.798

1.064

HG

21.96 ± 6.09