Table 1 Characteristics of the 6 included studies.

From: The comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention: a meta-analysis

First author (year)

Patients number (male %)

Age (years)

Study design

Study period

Approach strategy (%)

The definition of approach

The definition of technical/procedural success

Murakami T (2015)18

195 (84)

67 ± 11

Single center/retrospective

January 2008 to December 2011

N/A

TRA: single radial; TFA: single femoral or bifemoral

The percentage of diameter stenosis < 50% with TIMI-3 flow (procedural success)

Bakker EJ (2017)19

1253 (86)

65 ± 10

Multi-center/RECHARGE registry

January 2014 to October 2015

AWE (79.6%), ADR (15.3%), Retrograde (33.6%)

TRA: single radial or biradial; TFA: single femoral, bifemoral, or combined radial and femoral

The percentage of diameter stenosis < 30% with TIMI-3 flow (technical success)

Kinnaird T (2017)20

6480 (82)

64 ± 11

BCIS-NICOR database

January 2006 to December 2013

N/A

TRA: single radial or biradial; TFA: single femoral, bifemoral, or combined radial and femoral

N/A

Tanaka Y (2017)21

544 (82)

67 ± 11

Single center/retrospective

January 2005 to December 2014

Retrograde (22.4%)

TRA: single radial or biradial; TFA: single femoral, or bifemoral

The percentage of diameter stenosis < 50% with TIMI-3 flow (technical success)

Huyut MA (2018)22

358 (90)

60 ± 10

Single center/retrospective

January 2012 to August 2017

Antegrade (72.3%). Retrograde (27.7%)

TRA: single radial or biradial; TFA: single femoral, or bifemoral

The percentage of diameter stenosis < 30% with TIMI-3 flow (technical success) plus absence of in-hospital complications (procedural success)

Tajti P (2019)23

3790 (85)

65 ± 10

Multi-center/PROGRESS CTO registry

May 2012 to July 2018

AWE (83.6%), ADR (29.6%), Retrograde (36.7%)

TRA: single radial or biradial; TFA: single femoral, or bifemoral

The percentage of diameter stenosis < 30% with TIMI-3 flow (technical success) plus absence of in-hospital complications (procedural success)

  1. AWE antegrade wire escalation, ADR antegrade dissection and re-entry, TIMI thrombolysis in myocardial infarction.
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