Table 2 White blood cell counts and leukocyte subset indices.

	HC (22)	SS (53)	PMF (38)	P
Leukocytes*	6.3 ± 1.4	6.1 ± 1.7	6.4 ± 1.4	0.198^a
Monocytes*	0.5 ± 0.1	0.56 ± 0.2	0.6 ± 0.2	0.012^b HC vs. SS; = ns^c HC vs. PMF; = 0.008^c SS vs. PMF; = 0.032^c
Lymphocytes*	2.2 ± 0.6	1.7 ± 0.5	1.6 ± 0.4	0.001^a HC vs. SS; = 0.001^d HC vs. PMF; < 0.0001^c SS vs. PMF; = ns^d
Neutrophils*	3.4 ± 0.9	3.7 ± 1.4	4 ± 1.2	0.071^a
Platelets*	222.9 ± 40.6	239.8 ± 59.7	242.5 ± 40.6	0.334^b
NLR	1.6 ± 0.5	2.4 ± 1	2.7 ± 1.5	< 0.0001^a HC vs. SS; = 0.002^d HC vs. PMF; < 0.0001^d SS vs. PMF; = ns^d
PLR	108.3 ± 37.1	154.5 ± 54.8	160.5 ± 53.5	< 0.0001^a HC vs. SS; = 0.001^c HC vs. PMF; < 0.0001^d SS vs. PMF; ns^d
LMR	4.5 ± 1.5	3.1 ± 0.9	2.7 ± 1	< 0.0001^a HC vs. SS; < 0.0001^c HC vs. PMF; < 0.0001^d SS vs. PMF; = 0.044^d
SII	369.5 ± 157	567.3 ± 290.7	668.9 ± 424.7	< 0.0001^a HC vs. SS; = 0.002^d HC vs. PMF; < 0.0001^d SS vs. PMF; ns^d
SIRI	0.8 ± 0.4	1.3 ± 0.7	1.8 ± 1.2	< 0.0001^a HC vs. SS; = 0.002^d HC vs. PMF; < 0.0001^d SS vs. PMF; = 0.036^d
AISI	191.5 ± 109.6	330.8 ± 219.8	447.1 ± 314.1	< 0.0001a HC vs. SS; = 0.006^d HC vs. PMF; < 0.0001^d SS vs. PMF; = 0.044^d

NLR (neutrophil/lymphocyte ratio), PLR (platelet/lymphocyte ratio), LMR (lymphocyte/monocyte ratio), SII (neutrophil x platelet/lymphocyte ratio), SIRI (neutrophil x monocyte/lymphocyte ratio) and AISI (neutrophil x monocyte x platelet/lymphocyte ratio). *(× 10³ cell/µl). Data represent mean ± standard deviation. ^aKruskal–Wallis test, ^bANOVA, ^cStudent´s T-test, ^dMann–Whitney-U test. P, p value; ns non-significant.

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