Table 4 Between group findings.
Pre-treatment | Post-treatment | Difference | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
EG group | ET group | p value | EG group | ET group | p value | MD (CI) | F | Effect size (d) | p value | |
Avg ± SD | Avg ± SD | Avg ± SD | Avg ± SD | |||||||
Motor findings | ||||||||||
UPDRS | 13.63 ± 7.44 | 15.30 ± 8.83 | 0.839 | 6.90 ± 3.56 | 9.53 ± 9.16 | 0.771 | − 2.150 (− 8.166 to 3.866) | 0.143 | 0.006 | 0.708 |
BBT | 44.63 ± 9.67 | 44.23 ± 5.89 | 0.597 | 51.27 ± 5.93 | 53.30 ± 2.46 | 0.555 | − 0.815 (− 5.844 to 4.215) | 1.656 | 0.070 | 0.212 |
TUG | 14.90 ± 2.86 | 16.05 ± 6.95 | 0.862 | 13.01 ± 2.12 | 12.61 ± 5.44 | 0.622 | − 0.378 (− 4.167 to 3.411) | 0.843 | 0.037 | 0.368 |
6MWT | 198.90 ± 56.26 | 195.15 ± 75.36 | 0.816 | 283.63 ± 69.06 | 242.76 ± 76.35 | 0.283 | 22.311 (− 30.753 to 75.375) | 1.969 | 0.082 | 0.174 |
ABCS | 995.90 ± 351.10 | 1033.46 ± 335.29 | 0.839 | 1217.27 ± 352.13 | 1045.38 ± 402.31 | 0.385 | 67.168 (− 204.566 to 338.902) | 2.276 | 0.094 | 0.146 |
Cognition and mood | ||||||||||
MMSE | 26.36 ± 1.85 | 25.15 ± 2.79 | 0.292 | 26.63 ± 1.62 | 24.84 ± 3.50 | 0.291 | 1.500 (− 0.513 to 3.513) | 0.398 | 0.018 | 0.535 |
MoCA | 22.27 ± 2.19 | 22.76 ± 3.39 | 0.430 | 24.54 ± 1.50 | 23.00 ± 4.91 | 0.726 | 0.524 (− 2.177 to 3.226) | 5.308 | 0.186 | 0.035* |
GDS | 7.09 ± 6.13 | 10.46 ± 8.56 | 0.352 | 4.90 ± 3.23 | 9.00 ± 8.55 | 0.293 | − 3.731 (− 9.267 to 1.806) | 0.091 | 0.004 | 0.765 |
PDQ-39 | 42.72 ± 26.38 | 48.84 ± 24.82 | 0.562 | 24.72 ± 15.81 | 33.00 ± 27.53 | 0.772 | − 7.196 (− 24.706 to 10.315) | 0.042 | 0.002 | 0.840 |
Attention | ||||||||||
DS forward | 5.27 ± 0.90 | 5.57 ± 1.11 | 0.437 | 5.09 ± 1.04 | 5.15 ± 0.80 | 1.000 | − 0.180 (− 0.910 to 0.549) | 0.390 | 0.017 | 0.539 |
DS backward | 3.45 ± 1.21 | 3.41 ± 0.86 | 1.000 | 3.36 ± 0.92 | 3.23 ± 0.83 | 0.665 | 0.085 (− 0.635 to 0.805) | 0.660 | 0.003 | 0.799 |
Executive functions | ||||||||||
Stroop TD | 71.95 ± 27.96 | 68.25 ± 22.21 | 0.931 | 57.94 ± 23.81 | 65.50 ± 22.16 | 0.706 | − 1.931 (− 20.410 to 16.549) | 1.848 | 0.077 | 0.188 |
VF–fruit name pairs | 7.00 ± 0.89 | 5.76 ± 1.92 | 0.065 | 6.98 ± 1.67 | 6.92 ± 1.93 | 0.552 | 0.646 (− 0.624 to 1.917) | 3.335 | 0.132 | 0.081 |
Categorical fluency | 15.81 ± 5.94 | 15.15 ± 4.21 | 0.907 | 17.00 ± 6.61 | 16.07 ± 3.81 | 0.954 | 0.794 (− 3.311 to 4.898) | 0.029 | 0.001 | 0.867 |
Phonemic fluency | 23.81 ± 14.55 | 22.09 ± 12.89 | 0.505 | 24.00 ± 6.38 | 24.56 ± 7.68 | 0.908 | 0.581 (− 7.357 to 8.518) | 0.247 | 0.011 | 0.624 |
Abstract thinking | 2.72 ± 0.64 | 2.66 ± 0.62 | 0.567 | 2.63 ± 1.02 | 2.61 ± 0.65 | 0.677 | 0.039 (− 0.512 to 0.590) | 0.015 | 0.001 | 0.905 |
Similarities | 9.18 ± 1.07 | 7.72 ± 2.06 | 0.059 | 9.36 ± 1.20 | 8.92 ± 1.32 | 0.323 | 0.949 (− 0.146 to 2.044) | 2.695 | 0.109 | 0.115 |
CDT | 2.27 ± 0.64 | 3.00 ± 1.52 | 0.167 | 3.18 ± 0.98 | 2.67 ± 1.49 | 0.480 | − 0.111 (− 1.089 to 0.867) | 3.536 | 0.138 | 0.073 |
Memory | ||||||||||
Visual immediate recall | 5.45 ± 3.35 | 6.61 ± 4.03 | 0.466 | 7.36 ± 3.29 | 8.37 ± 5.83 | 0.884 | − 1.088 (− 4.326 to 2.151) | 0.008 | 0.000 | 0.932 |
Visual delayed recall | 3.09 ± 2.21 | 6.07 ± 4.62 | 0.143 | 7.00 ± 3.68 | 7.00 ± 4.83 | 0.907 | − 1.493 (− 4.708 to 1.722) | 6.358 | 0.224 | 0.019* |
Visual recognition | 1.81 ± 0.87 | 1.84 ± 1.67 | 0.881 | 3.09 ± 0.70 | 2.84 ± 1.40 | 0.927 | 0.110 (− 0.767 to 0.987) | 0.217 | 0.010 | 0.646 |
Logical immediate recall | 14.63 ± 4.52 | 12.47 ± 3.61 | 0.139 | 13.07 ± 3.51 | 10.83 ± 4.48 | 0.163 | 2.204 (− 0.658 to 5.066) | 0.002 | 0.000 | 0.967 |
Logical delayed recall | 14.36 ± 4.94 | 12.36 ± 5.13 | 0.296 | 12.51 ± 4.03 | 11.29 ± 5.66 | 0.560 | 1.613 (− 1.940 to 5.165) | 0.118 | 0.005 | 0.735 |
VMPT immediate recall | 3.00 ± 1.18 | 4.23 ± 1.69 | 0.017* | 4.18 ± 1.25 | 4.00 ± 1.35 | 0.633 | − 0.524 (− 1.421 to 0.372) | 3.537 | 0.139 | 0.073 |
VMPT delayed recall | 7.09 ± 2.50 | 5.53 ± 3.33 | 0.254 | 6.81 ± 3.99 | 8.07 ± 4.29 | 0.337 | 0.147 (− 2.515 to 2.809) | 3.579 | 0.140 | 0.072 |
VMPT recognition | 4.18 ± 1.60 | 4.15 ± 3.67 | 0.539 | 4.27 ± 2.28 | 3.38 ± 2.02 | 0.113 | 0.685 (− 0.889 to 2.260) | 0.824 | 0.036 | 0.374 |
VMPT Total | 11.36 ± 2.20 | 9.69 ± 4.66 | 0.641 | 11.54 ± 3.77 | 11.46 ± 4.23 | 0.883 | 0.878 (− 2.007 to 3.762) | 1.032 | 0.045 | 0.321 |
Language | ||||||||||
BNT | 22.81 ± 4.06 | 25.39 ± 4.76 | 0.115 | 25.90 ± 3.75 | 25.92 ± 5.20 | 0.705 | − 1.297 (− 5.005 to 2.412) | 6.551 | 0.229 | 0.018* |
Visual spatial functions | ||||||||||
BFR | 42.72 ± 4.10 | 40.92 ± 3.66 | 0.321 | 41.27 ± 2.14 | 40.07 ± 5.00 | 0.540 | 1.500 (− 1.531 to 4.531) | 0.209 | 0.009 | 0.652 |
Line orientation | 42.08 ± 10.44 | 41.76 ± 13.94 | 0.727 | 48.79 ± 5.93 | 44.97 ± 11.13 | 0.523 | 2.067 (− 5.968 to 10.103) | 0.642 | 0.028 | 0.432 |