Figure 1
From: Determining KLF14 tertiary structure and diagnostic significance in brain cancer progression
Expression and diagnostic significance of TPD52, PKCε, KLF14 and miRNA 124. Expression of (A) TPD52 (B) PKCε (C) KLF14 and (D) miR-124 in brain tumor patients compared to healthy controls. There is up-regulated expression of TPD52, and PKCε (P = 0.0015, P = 0.0046 respectively) and down-regulated expression of KLF14 and miRNA124 (P = 0.0025, P = 0.0010 respectively) in brain tumor patients compared to healthy controls. Representative data were presented as mean ± SEM of triplicate experiments and **refers to P value less than 0.05 and ***refers to P value less than or equal to 0.001. Statistical significance was measured by two-way ANOVA. ROC curve for TPD52, PKCε, KLF14 and miR-124 predicted high risk for brain tumor. Area under the ROC curve (AUC) for (E) TPD 52 was 0.69 and 95% confidence interval (CI) was 0.6236 to 0.7758. AUC for (F) PKCε was 0.564 and 95% CI was 0.4804 to 0.6476. AUC for (G) KLF14 was 0.86 and 95% CI was 0.8057 to 0.9143. AUC for (H) miR-124 was 0.8420 and 95% CI was 0.7858 to 0.8982.
