Table 2 The effects of asthma and its coexisting respiratory comorbidities on mortality in patients with asthma compared with subjects without asthma.
Ā | Unadjusted model | Model 1 | Model 2 | |||
---|---|---|---|---|---|---|
All-cause | Respiratory | All-cause | Respiratory | All-cause | Respiratory | |
HR (95% CI) | HR (95% CI) | aHR (95% CI) | aHR (95% CI) | aHR (95% CI) | aHR (95% CI) | |
COPD | ||||||
Control cohort | Reference | Reference | Reference | Reference | Reference | Reference |
Asthma cohort without COPD | 0.76 (0.72ā0.81) | 1.21 (1.01ā1.44) | 0.95 (0.90ā1.01) | 1.58 (1.32ā1.89) | 0.94 (0.89ā1.00) | 1.53 (1.28ā1.84) |
Asthma cohort with COPD | 2.94 (2.75ā3.14) | 9.31 (7.99ā10.85) | 1.49 (1.39ā1.59) | 4.27 (3.66ā4.99) | 1.46 (1.36ā1.56) | 3.95 (3.38ā4.61) |
Pneumonia | ||||||
Control cohort | Reference | Reference | Reference | Reference | Reference | Reference |
Asthma cohort without pneumonia | 0.99 (0.94ā1.04) | 1.97 (1.70ā2.29) | 1.03 (0.98ā1.09) | 2.08 (1.79ā2.41) | 1.02 (0.97ā1.08) | 1.99 (1.71ā2.30) |
Asthma cohort with pneumonia | 1.92 (1.75ā2.09) | 5.92 (4.88ā7.19) | 1.59 (1.46ā1.74) | 4.72 (3.89ā5.73) | 1.56 (1.42ā1.70) | 4.33 (3.57ā5.27) |
Bronchiectasis | ||||||
Control cohort | Reference | Reference | Reference | Reference | Reference | Reference |
Asthma cohort without bronchiectasis | 1.09 (1.03ā1.14) | 2.32 (2.03ā2.65) | 1.12 (1.06ā1.17) | 2.38 (2.08ā2.72) | 1.10 (1.05ā1.16) | 2.26 (1.98ā2.59) |
Asthma cohort with bronchiectasis | 2.50 (2.07ā3.02) | 11.70 (8.47ā16.18) | 1.43 (1.18ā1.73) | 6.35 (4.59ā8.78) | 1.39 (1.15ā1.68) | 5.74 (4.15ā7.95) |
Lung cancer | ||||||
Control cohort | Reference | Reference | Reference | Reference | Reference | Reference |
Asthma cohort without lung cancer | 1.11 (1.06ā1.16) | 2.53 (2.22ā2.87) | 1.12 (1.07ā1.18) | 2.55 (2.24ā2.90) | 1.11 (1.05ā1.16) | 2.41 (2.11ā2.74) |
Asthma cohort with lung cancer | 7.30 (4.60ā11.58) | 5.34 (0.75ā37.94) | 4.11 (2.59ā6.52) | 3.25 (0.46ā23.09) | 4.07 (2.57ā6.46) | 3.12 (0.44ā22.10) |