Table 3 Perfect-scoring targets with pharmacological applications used for virtual screening in the drug repurposing Hub and ChemBL databases.

From: Predicting target–ligand interactions with graph convolutional networks for interpretable pharmaceutical discovery

Acronym

Target protein

Pharmacological application

FPPS

Farnesyl pyrophosphase synthase

Anticancer and Antimicrobial

GCR

Glucocorticoid receptor

Anti-inflammatory

GRIK1

Glutamate ionotropic receptor kainate 1

Neurophysiological

KITH

Thymidine kinase

Anticancer and Antimicrobial

PNPH

Purine nucleoside phosphorylase

Anticancer

SAHH

Adenosylhomocysteinase

Anti-inflammatory

PA2GA

Phospholipase A2

Anticancer

CXCR4

C-X-C chemokine receptor type 4

Antibacterial and Anticancer

ADA

Adenosine deaminase

Immunomodulation

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