Table 2 ICU interventions and co-interventions in patients with heart failure who were randomized to intermittent pneumatic compression with pharmacologic thromboprophylaxis (IPC group) or pharmacologic thromboprophylaxis alone (control group).
IPC group (N = 133) | Control group (N = 142) | p value | |
|---|---|---|---|
Median no. of days of the trial intervention (Q1, Q3) | 7 (4,15) | 7 (4,12) | 0.65 |
Use of pneumatic compression | |||
Patients receiving pneumatic compression at least for one day, n (%) | 131 (98.5) | 13 (9.2) | < 0.0001 |
Daily duration of pneumatic compression (h)—median (Q1, Q3) | 22 (21, 22) | 0 (0, 0) | < 0.0001 |
Use of foot pumps—n (%) | 12 (9.0) | 1 (0.7) | 0.001 |
Knee-length | 120 (90.2) | 13 (9.2) | < 0.0001 |
Thigh-length | 11 (8.3) | 0 (0) | |
Organ support—n (%) | |||
Mechanical ventilation | 98 (73.7) | 98 (69.0) | 0.39 |
Vasopressors | 80 (60.2) | 71 (50.0) | 0.09 |
Renal replacement therapy | |||
Continuous renal replacement | 29 (21.8) | 17 (12.0) | 0.03 |
Intermittent dialysis | 8 (6.0) | 11 (7.7) | 0.57 |
Peritoneal dialysis | 0 | 1 (0.7) | 1.0 |
Pharmacologic prophylaxis—n (%) | |||
Prophylactic UFH | 110 (82.7) | 114 (80.3) | 0.61 |
Prophylactic LMWH | 29 (21.8) | 34 (23.9) | 0.67 |
Therapeutic anticoagulation after randomization for reasons other than venous thromboembolism—n (%) | 15 (11.3) | 15 (10.6) | 0.85 |
Duration (days)—median | 5 (2, 11) | 3 (2, 5) | 0.25 |
Warfarin—n (%) | 1 (0.8) | 2 (1.4) | 1.0 |
Other oral anticoagulants—n (%) | 2 (1.5) | 2 (1.4) | 1.0 |
Argatroban—n (%) | 0 | 1 (0.7) | 1.0 |
Antiplatelet therapy—n (%) | |||
Aspirin | 75 (56.4) | 74 (52.1) | 0.48 |
Clopidogrel | 29 (21.8) | 31 (21.8) | 1.0 |
Statin therpay—n (%) | 72 (54.1) | 74 (52.1) | 0.74 |
Central venous catheters*—n (%) | 92 (69.2) | 97 (68.3) | 0.88 |
Femoral central venous catheters– n (%) | 43 (32.3) | 39 (27.5) | 0.38 |
Jugular or subclavian | 74 (55.6) | 74 (52.1) | 0.56 |
Peripherally inserted central catheter | 19 (14.3) | 15 (10.6) | 0.35 |
None | 41 (30.8) | 45 (31.7) | 0.88 |
Diagnostic imaging | |||
Lower limb ultrasound per patient, median (Q1, Q3) | 2 (1, 4) | 2 (1, 4) | 0.54 |
Ultrasonography for upper limb and neck to evaluate for thrombosis—n (%) | 5 (3.8) | 4 (2.8) | 0.74 |
Chest CT for PE—n (%) | 5 (3.8) | 7 (4.9) | 0.64 |
Ventilation/perfusion scan of the lungs—n (%) | 0 | 0 | |
Abdominal CT—n (%) | 9 (6.8) | 5 (3.5) | 0.22 |
Transthoracic echocardiograms—n (%) | 19 (14.3) | 24 (16.9) | 0.55 |
Transesophageal echocardiograms—n (%) | 1 (0.8) | 1 (0.7) | 1.0 |
