Figure 1 | Scientific Reports

Figure 1

From: Integrated analysis of an in vivo model of intra-nasal exposure to instilled air pollutants reveals cell-type specific responses in the placenta

Figure 1

(a) Schematic representation of mouse placenta and location of various cell types in different placental compartments. (b) Uniform Manifold Approximation and Projection (UMAP) plot of cell and tissue clusters detected in scRNAseq in all 6 samples. Sub-clusters of related cell types could be detected for immune cells, decidual cells, endo/epithelial-like cells, erythroid cells and trophoblasts. (c) UMAP projection of cells originating from air pollution (AP) samples (n = 3) and control (CON) samples (n = 3). (d, e) Quantification of each cell type by placental layer, decidual, junctional and labyrinthine (d) or treatment groups, namely AP and CON (e). Cell counts were normalized by the total cell count per sample and depicted as fractions of the total cell count for each cell/tissue type.

Back to article page