Figure 4
From: Stress-induced despair behavior develops independently of the Ahr-RORγt axis in CD4 + cells
Loss of Rorc in T cells does not Impact Depressive- or Anxiety- like Behaviors in Female Mice. No differences in (A) depressive-like (n = 12/group) or (B) anxiety-like (n = 12/group) behaviors between female Rorc KO and littermate controls at baseline. No differences in the (C) Kullback–Leibler divergence heatmap or (D) PCA plot of DeepLabCut analyzed baseline behaviors between groups (n = 12/group). (E) Depressive-like (n = 12/group) and (F) anxiety-like (n = 12/group) behaviors after 3 weeks of UCRS between female Rorc KO and littermate controls (Nestlet Shred: p = 0.0392, Elevated Plus Maze: p = 0.0453). (G) Kullback–Leibler divergence heatmap and (H) PCA plot of DeepLabCut analyzed behaviors after 3 weeks of UCRS between groups (n = 12/group). T tests, N = 1, female mice.
