Figure 5

Bronchial tissue of HDM-sensitized AregKO mice. (a) Optical microscope image (HE stained) and b) SEM image (Grocott stained) of pulmonary tissue (c) optical microscope image (HE stained) and (d) SEM image (Grocott stained) of Br and Ar. (e) Higher magnified optical image (HE stained) and (f) SEM image (Grocott stained) of Br. (a, b) Weak peribronchial fibrosis throughout. (c–f) Little perivascular fibrosis and no spillover into the peribronchial area. Wide interstitial space. All scale bars show 100 μm length.