Figure 4

ECM derived from cytokine-treated hRP causes induction of hRMEC adhesion molecules. Naïve hRMEC were plated onto ECM derived from TNFα- or IL-1β-treated hRP. hRMEC were collected and assayed for expression of (A) E-selectin (gene name: SELE), (B) ICAM-1, or (C) VCAM-1. Expression data are reported as fold induction over vehicle with bars representing mean ± SD (vehicle: n = 4; TNFα: n = 5; IL-1β: n = 4).