Table 4 Association of baseline factor level with 90-Day change in NT-proBNP.

From: Plasma metabolites associated with functional and clinical outcomes in heart failure with reduced ejection fraction with and without type 2 diabetes

Factor

Overall estimate

P-value

Diabetic estimate

P-value

Non-diabetic estimate

P-value

Basic

1

268.651

0.505

− 164.308

0.719

1228.465

0.104

2

− 228.426

0.387

− 291.548

0.348

− 25.689

0.958

4

− 174.252

0.737

− 204.213

0.763

− 311.809

0.703

5

65.615

0.791

− 222.873

0.459

495.399

0.242

7

− 15.614

0.951

− 588.263

0.057

749.912

0.086

8

757.495

0.005

514.046

0.100

1222.194

0.013

11

100.557

0.684

− 477.538

0.121

542.204

0.208

13

247.111

0.402

− 144.919

0.695

546.801

0.280

Fulla

8

607.423

0.052

435.181

0.252

1193.632

0.042

  1. Significant values are in bold.
  2. aModel: change in NT-proBNP (D90 – baseline) ~ Baseline factor + baseline NT-proBNP + age + sex + race + randomization drug + BMI + baseline creatinine + SBP + liver function tests + diabetes (overall only).
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