Table 1 Clinical characteristics of 10 cases with bilateral adrenal accumulation with MIBG and a mild increase in CA or MN.
Case | Unit | Standard value | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | Median [range] |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sex | Male | Female | Male | Male | Male | Female | Male | Male | Male | Male | |||
Age | Years | 59 | 46 | 47 | 66 | 41 | 64 | 72 | 47 | 83 | 37 | 53 [46–66] | |
Plasma Ad | ng/mL | 0.00–0.17 | 0.14 | 0.09 | 0.10 | 0.00 | 0.02 | 0.09 | 0.02 | 0.04 | 0.04 | 0.00 | 0.04 [0.02–0.09] |
Plasma NA | ng/mL | 0.15–0.57 | 0.45 | 0.97 | 0.62 | 0.58 | 0.02 | 0.55 | 1.00 | 0.04 | 1.20 | 0.00 | 0.57 [0.46–0.89] |
Urinary MN | mg/day | 0.05–0.20 | 0.31 | 0.22 | 0.20 | 0.19 | 0.26 | 0.22 | 0.22 | 0.12 | 0.22 [0.20–0.23] | ||
Urinary NMN | mg/day | 0.10–0.28 | 0.22 | 0.19 | 0.29 | 0.67 | 0.23 | 0.42 | 0.37 | 0.37 | 0.33 [0.23–0.38] | ||
HbA1c | % | 5.7 | 5.6 | 5.7 | 5.9 | 6.0 | 8.1 | 5.2 | 5.7 | 6.0 | 6.3 | 5.8 [5.7–6.0] | |
Hypertension | + | + | + | + | − | + | + | + | + | + | |||
Symptoms | |||||||||||||
Palpitation | + | + | + | − | − | − | + | − | + | − | |||
Headache | − | + | − | + | − | + | − | − | − | − | |||
Weight loss | + | − | + | − | − | − | – | – | – | – | |||
Constipation | – | – | – | + | – | + | – | – | – | – | |||
Adrenal tumor | + | + | + | + | + | – | – | – | – | – | |||
Tumor size | mm | 16 | 42 | 36 | 12 | 27 | |||||||
CT value of the tumor | HU | − 5 | 13 | 45 | NA | 29 | |||||||
MIBG uptake intensity | |||||||||||||
A/L ratio | 1.64 | 1.35 | 1.12 | 1.49 | 1.09 | 1.50 | 1.05 | 1.46 | 1.19 | 2.33 | 1.29 [1.13–1.67] | ||
Lateral adrenal ratio | 1.42 | 1.47 | 1.14 | 1.32 | 1.07 | 1.27 | 1.18 | 1.01 | 1.05 | 1.94 | 1.22 [1.09–1.39] | ||
