Figure 2 | Scientific Reports

Figure 2

From: Overexpression of alanine-glyoxylate aminotransferase 2 protects from asymmetric dimethylarginine-induced endothelial dysfunction and aortic remodeling

Figure 2

(a) Distribution of AGXT2 transgene in different tissues of TG mice, detected by Western blotting. (b) Distribution of AGXT2 transgene in various tissues of TG mice, detected by qPCR, n = 5–7 per group. (c) Expression of total (endogenous and transgenic) AGXT2 in kidney and liver of transgenic and wild-type mice. (d) Expression of DDAH1 and DDAH2 (e) in various tissues of TG mice, detected by qPCR. *p < 0.05; ***p < 0.001; One-way ANOVA followed by Tukey’s multiple comparison test (c–e). N = 6–7 (a), 5–7 (b–d). Cohen’s d = (c) 1.7 (kidney) and 10.2 (liver), (d) 3.4 (brain) and 2.2 (spleen); (e) 2.3 (spleen).

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