Figure 3

Biochemical analysis of metabolites in wild-type (WT) and AGXT2 transgenic (TG) mice. (a) Plasma levels of ADMA and ADGV (b) Urine levels of ADMA and ADGV (c) Content of ADMA and ADGV in the heart (d) Content of ADMA and ADGV in the lung. *p < 0.05; ***p < 0.001. One-way ANOVA followed by Tukey’s multiple comparison test. N = 22 (a), 5–6 (b), 4 (c,d). Cohen’s d = (a) 0.7 (ADMA) and 2.9 (ADGV), (b) 1.4, (c) 3.5 (ADMA) and 4.7 (ADGV); (d) 2.4 (ADMA) and 4.6 (ADGV).