Figure 3

Rankings of interactions involving peptide-target pairs. (A) Distributions of ranks of the peptide-target pairs are shown for models whose training data included interactions involving an endogenous peptide analog (optimistic scenario; +) and models trained without (pessimistic scenario; −). The ranks of the true targets for two therapeutic peptides are illustrated on their one-to-all curves on the right side of the box plot. (B) Counts of therapeutic peptide targets ranking in the top 1% on the corresponding one-to-all curve.