Table 1 Clinicopathological characteristics.

From: Next-generation sequencing in advanced Chinese melanoma reveals therapeutic targets and prognostic biomarkers for immunotherapy

 

CSD/NCSD

n = 41 (%)

Mucosal

n = 25 (%)

Acral

n = 15 (%)

p value

Median age (range)

44 (36–59)

53 (48–64)

55 (50–60)

0.085

Gender (%)

   

0.315

Male

23 (56.1)

12 (48.0)

5 (33.3)

 

Female

18 (43.9)

13 (52.0)

10 (66.7)

 

Stage (%)

   

0.047

IA

1 (2.9)

0 (0)

0 (0)

 

IIA

1 (2.9)

2 (10)

2 (13.3)

 

IIB

5 (14.7)

3 (15.0)

0 (0)

 

IIC

3 (8.8)

1(5.0)

5 (33.3)

 

IIIA

0 (0)

3(15.0)

0 (0)

 

IIIB

2 (5.9)

2(10.0)

0 (0)

 

IIIC

15 (44.1)

3(15.0)

5 (33.3)

 

IV

7 (20.6)

6 (30.0)

3 (20.0)

 

Sample type (%)

   

0.584

Primary

35(85.4)

21 (84.0)

11 (73.3)

 

Metastatic

6(14.6)

4 (16.0)

4 (26.7)

 

Ulceration (%)

   

0.020

0

30 (73.2)

17 (68.0)

5 (33.3)

 

1

11 (26.8)

8 (32.0)

10 (66.7)

 

Congenital nevus (%)

   

0.001

0

26 (63.4)

25 (100.0)

14 (93.3)

 

1

15 (36.6)

0 (0)

1 (6.7)

 

Trauma (%)

   

0.014

0

34 (82.9)

24 (96.0)

9 (60.0)

 

1

7 (17.1)

1 (4.0)

6 (40.0)

 

Sun exposure (%)

   

0.001

0

29 (70.7)

25 (100.0)

15 (100.0)

 

1

12 (29.3)

0 (0)

0 (0)

 
  1. *P values < 0.05 in bold are statistically significant.