Table 1 Genotypic and allelic freuencies of PON1 rs854560 in study subjects with OPs and PYR pesticide toxicity.

From: Insights of OPs and PYR cytotoxic potential Invitro and genotoxic impact on PON1 genetic variant among exposed workers in Pakistan

SNP

Genotype n = 250

Exposed n = 100

Control n = 150

Chi-square

p-value

PON1 rs854560

TT

24 (24%)

77 (51%)

22.9

0.001***

TA

74 (74%)

65 (43%)

AA

2 (2%)

8 (5%)

Alleles

n = 200

n = 300

Odds ratio (95%CI)

p-value

T

122 (61%)

146 (48%)

0.473 (0.25- 0.87)

0.016

A

78 (39%)

54 (18%)

  
  1. Significance p < 0.05.
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