Figure 1
From: TACSTD2 upregulation is an early reaction to lung infection
TACSTD2 expression in cell clusters of human lungs identified by single cell RNA sequencing. (a) RNA expression (nTPM) in the cell type clusters identified in lungs visualized by a bar chart, retrieved from Human Protein Atlas. Single cell transcriptomic dataset of Vieira Braga et al. (GSE130148)30 was used. (b) Cell clusters with significantly (p adj < 0.05) enriched TACSTD2 expression as identified in human lungs by Travaglini et al.31. Chart shows the natural log of the average fold change between the indicated cell type and other cell types in lungs. Differentially expressed genes were identified using the ‘MAST’ statistical framework implemented in Seurat’s ‘FindMarkers’ function by Travaglini et al.31. c cluster number, with main cell type annotated, n number of included cell, **p adj < 0.01, ***p adj < 0.001, p adj p-value with Bonferroni correction applied.
