Figure 5

Tacstd2 expression is increased in lung epithelial cells after infection. Tacstd2 expression in (a) sorted EpCAM⁺CD31⁻CD45⁻ LECs from wt and Ifnlr^−/− mice infected or not with influenza virus X31 at 8 days after infection (GSE148709)³⁶, shown as normalized counts per gene per sample (generated by DESeq2) and (b) sorted EpCAM⁺CD45⁻ LECs from mice infected or not with Streptococcus pneumoniae at 15 h after infection (GSE71623), shown as log2-transformed, RMA (Robust Multiarray Average)-normalized gene expression values³⁷. Significant differences (***p < 0.001; ****p < 0.0001; unpaired t-test) are indicated.