Table 2 Genotype comparison between the TE biopsy and the corresponding embryo. “B” denotes biopsied sample, and “E” indicates the corresponding remaining embryo. WT refers to the MYO7A wild-type sequence. Bold letters indicate insertions and dashes represent deletions. The underline indicates gRNA protospacer sequence and red letters represent the PAM sequence.

From: CRISPR/Cas9 editing of the MYO7A gene in rhesus macaque embryos to generate a primate model of Usher syndrome type 1B

  1. aWT and Edited sequence percentages do not necessarily add up to 100% because some sequencing results included low quality reads or other sequencing artifacts not aligning to the correct rhesus macaque MYO7A reference sequence.
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