Figure 5 | Scientific Reports

Figure 5

From: Cell type specific cannabinoid CB1 receptor distribution across the human and non-human primate cortex

Figure 5

Mean CB1R intensity within excitatory (vGlut1-IR +) and inhibitory (vGAT1-IR +) cell types across three brain regions of the postmortem human cortex. Each individual data point represents mean intensity averaged across all sampled sites across a cortical layer. There was a main effect of cell type, p < 0.001, main effect of brain region, p < 0.001, and a significant cell type × brain region interaction, p < 0.001. Post hoc analysis indicated significantly lower mean CB1R intensity within the PFC for both excitatory and inhibitory populations compared to the primary and association auditory cortex, p < 0.001 for all comparisons. Straight lines indicate main effects across groups. Brackets indicate post hoc pairwise comparisons. **p < 0.001. Error bar denotes SEM. PFC = prefrontal cortex, A1 = primary auditory cortex, A2 = association auditory cortex.

Back to article page