Table 1 Calculated volume and measured volume for the different glioblastoma compartments (114 MRIs).

From: Ellipsoid calculations versus manual tumor delineations for glioblastoma tumor volume evaluation

 

Calculated volume (CV) (diameters 3D) (cm3)

Measured volume (MV) (delineation) (cm3)

Difference CV − MV (cm3)

((CV − MV)/CV)*100 (%)

 

CV (diameters 3D) (cm3)

MV (delineation) (cm3)

Difference CV − MV (cm3)

((CV − MV)/CV)*100

(%)

CE total

CE before CRT

Mean

Median

Range

41.6

27.9

0.6 to 167.6

15.5

11.2

0.3 to 66.0

26.1

17.9

−0.2 to 117.3

174.9

162.1

−26.1 to 398.5

Mean

Median

Range

37.1

26.7

2.4 to 167.6

12.6

9.2

1.2 to 66.0

24.9

18.7

0.8 to 117.3

196.6

189.3

6.9 to 398.5

CE at suspicion of progression

Mean

Median

Range

46.1

31.0

0.6 to 159.6

18.3

11.5

0.3 to 60.7

27.8

17.5

−0.2 to 115.3

153.2

145.3

−26.10 to 392.1

NEC total

NEC before CRT

Mean

Median

Range

17.5

6.3

0.0 to 128.1

7.3

2.4

0.0 to 42.4

10.1

3.0

−0.1 to 95.9

150.3

111.3

−10.7 to 789.3

Mean

Median

Range

15.4

3.6

0.0 to 128.1

5.9

1.5

0.0 to 39.8

9.6

1.7

−0.1 to 95.9

165.4

125.6

−10.7 to 789.3

NEC at suspicion of progression

Mean

Median

Range

19.5

9.9

0.0 to 106.6

8.8

3.6

0.0 to 42.4

10.7

5.3

0.0 to 70.3

139.9

100.8

20.8 to 615.8

GTV total

GTV before CRT

Mean

Median

Range

58.7

52.7

1.2 to 145.8

47.6

39.8

1.0 to 128.2

11.1

8.8

−28.9 to 67.0

26.1

22.1

−68.8 to 207.2

Mean

Median

Range

54.7

47.0

5.1 to 145.0

42.8

36.4

4.1 to 107.9

11.9

9.0

−12.7 to 53.6

30.5

26.4

−24.1 to 117.6

GTV at suspicion of progression

Mean

Median

Range

62.2

55.6

1.2 to 145.8

52.4

53.2

1.0 to 128.2

10.3

6.00

−28.9 to 67.0

21.7

15.0

−68.8 to 207.2

FLAIR total

FLAIR before CRT

 

Mean

Median

Range

179.2

142.0

13.7 to 722.9

132.3

110.8

13.6 to 520.2

46.9

32.4

−53.3 to 222.5

38.2

34.2

−34.5 to 172.2

Mean

Median

Range

129.7

94.5

13.7 to 505.3

95.9

73.4

13.6 to 339.3

33.8

23.9

−50.4 to 189.1

38.5

32.1

−34.5 to 172.1

FLAIR at suspicion of progression

Mean

Median

Range

228.7

200.1

30.7 to 722.9

168.8

146.3

21.3 to 520.2

59.9

50.6

−53.3 to 222.5

37.9

39.0

−29.5 to 113.3

  1. Calculated volume (CV) and measured volume (MV) and difference between the two measurement methods for the CE, the NEC, the GTV, and the FLAIR compartments for the 114 MRIs: the 57 MRIs before CRT and the 57 MRIs showing a suspicion of progression.
  2. CE contrast-enhancement, GTV gross target volume, NEC necrosis area.