Figure 5
From: Immuno-reactive cancer organoid model to assess effects of the microbiome on cancer immunotherapy
The effects of bacterial metabolites on immune responses in iTOs. (a–c) CD8 (a), Granzyme B (b), and cleaved caspase-3 signals (c) normalized to DAPI signal in iTOs (n = 4 ROI). (d) The effects of bacterial metabolites on CD8+ immune cell population viability (data representative of 3 organoids combined).
