Table 3 Univariate and multivariate analysis of factors associated with BOS change of temporal ONH.

From: Waveform changes of laser speckle flowgraphy in the temporal optic nerve head and peripapillary atrophy after trabeculectomy in open-angle glaucoma

Independent variables

Univariate

Multivariate (IOP, MAP)

Multivariate (OPP)

Time, month

0.48 (0.45), 0.28

  

Sex, male versus female

4.9 (2.3), 0.033*

  

Hypertension

0.068 (2.4), 0.98

  

No. of baseline antiglaucoma eye drops

 − 3.5 (1.7), 0.040*

  

Age, year

 − 0.12 (0.14), 0.39

  

Baseline axial length, mm

 − 0.31 (1.1), 0.78

  

Baseline mean deviation, dB

0.12 (0.21), 0.58

  

Baseline BOS, AU

 − 0.59 (0.063), < 0.001*

 − 0.55 (0.055), < 0.001*

 − 0.61 (0.057), < 0.001*

Baseline MT, AU

 − 0.18 (0.53), 0.74

  

MT change, AU

0.22 (0.42), 0.61

0.33 (0.31), 0.29

0.26 (0.35), 0.45

IOP change, mmHg

 − 0.48 (0.12), < 0.001*

 − 0.35 (0.089), < 0.001*

 

MAP change, mmHg

0.0046 (0.061), 0.94

  

OPP change, mmHg

0.18 (0.082), 0.025*

 

0.21 (0.065), 0.001*

Pulse rate change, beats/min

0.092 (0.052), 0.076

0.096 (0.044), 0.030*

0.11 (0.051), 0.038*

Disc area, mm2

 − 3.0 (5.7), 0.60

  

Difference in LSFG measurement time

0.59 (5.7), 0.92

2.7 (4.5), 0.54

 − 2.7 (5.3), 0.62

  1. Multivariate analysis was performed in two groups, one containing IOP and MAP and one containing OPP. The results are listed in the order of coefficient (standard error) and P-value.
  2. BOS blow out score, ONH optic nerve head, MT average mean blur rate in tissue area, IOP intraocular pressure, MAP mean arterial pressure, OPP Ocular Perfusion Pressure, LSFG Laser speckle flowgraphy.
  3. *P < 0.05.
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