Table 3 Median age and time post-ingestion [IQR] distribution of three major outcomes of 13 toxicology referral centers during early Iranian methanol outbreak (n = 716).

From: A cross-sectional multicenter linkage study of hospital admissions and mortality due to methanol poisoning in Iranian adults during the COVID-19 pandemic

Province

East Azarbayjan (n = 140)

Gilan (n = 28)

Hamedan (n = 7)

Isfahan (n = 52)

Khorasan Razavi (n = 56)

Khuzestan (n = 75)

Mazandaran (n = 5)

Qazvin (n = 3)

Tehran (n = 316)

West Azarbayjan (n = 4)

Yazd (n = 30)

P value

Total (n = 716)

Dead (n = 84)

Age (year)

43 [36, 50]

42 [35, 57]

43 [43, 43]

30 [27, 35]

23 [–, –]

36 [30, 40]

32 [32, –]

45 [–, –]

39 [34, 48]

36 [–, –]

–

0.046*

39 [32, 46]

Time of admission post-ingestion (hour)

24 [24, 48]

24 [11, 42]

7 [–, –]

27 [23, 32]

ND

48 [48, 72]

24 [24, –]

24 [–, –]

24 [24, 24]

36 [–, –]

–

0.012‡

24 [24, 48]

n (%)

19/140 (13.6)

11/28 (39.3)

1/7 (14.3)

5/52 (9.6)

1/56 (1.8)

7/75 (9.3)

3/5 (60)

1/3 (33.3)

35/316 (11.1)

1/4 (25)

0

 < 0.001†

84/716 (11.7)

Survival with no sequelae (n = 492)

(Age year)

31 [26, 38]

39 [31, 49]

32 [25, 45]

30 [24, 36]

28 [21, 35]

29 [24, 30]

27 [–, –]

21 [19,–]

32 [26, 43]

27 [27, 27]

26 [24, 30]

 < 0.001*

30 [25, 38]

Time of admission post-ingestion (hour)

48 [24, 48]

30 [6, 66]

87 [5, –]

36 [19, 43]

24 [12, 48]

48 [24, 48]

36 [–, –]

48 [48, 48]

24 [24, 24]

24 [36, 48]

21 [12, 24]

0.888‡

45 [24, 48]

n (%)

105 (75.0)

10/28 (35.7)

6/7 (85.7)

37 (71.2)

40 (50.6)

66/77 (88)

1/5 (20)

2/3 (66.7)

212/316 (27.1)

1/4 (25)

14/30 (46.7)

 < 0.001†

492/716 (68.7)

Survival with sequelae (n = 140)

Age (year)

38 [32, 47]

38 [24, 60]

47 [30, –]

33 [24, 39]

31 [25, 37]

41 [28, –]

60 [–, –]

36 [36, 36]

34 [27, 40]

62 [–, –]

26 [24, 33]

0.011*

33 [26, 40]

Time of admission post-ingestion (hour)

24 [24, 48)

72 [20, 96)

0

36 [24, 65)

48 [17, 48)

48 [48, 48)

24 [–, –)

0

48 [24, 48)

13 [–, –)

12 [6, 14)

0.031‡

48 [24, 48)

n (%)

16 (11.4)

7/28 (25)

0

10/52 (19.2)

38/56 (67.9)

2/75 (2.7)

1/5 (20)

0

69/316 (21.8)

2/4 (50)

16/30 (53.3)

 < 0.001†

140/716 (19.6)

P value*

§

 < 0.001

0.750

0.494

0.956

0.150

0.006

0.186

0.259

0.008

0.259

0.625

–

–

0.168

0.132

0.999

0.341

0.280

0.760

0.264

0.999

0.001

0.264

0.200

–

0.009

Total (n = 716)

Age (year)

35 [28, 42]

41 [32, 55]

33 [28, 52]

30 [24, 36]

29 [23, 36]

29 [25, 32]

32 [30, 49]

29 [20,43]

34 [28, 42]

47 [33, 60]

26 [25, 30]

 < 0.001*

32 [26, 40]

Time of admission post-ingestion (hour)

48 [24, 48]

24 [10, 54]

7 [4, 96]

34 [22, 45]

24 [12, 48]

48 [24, 48]

24 [24, 33]

48 [30, 48]

48 [24, 48]

30 [19, 39]

14 [11, 23]

 < 0.001*

40 [24, 48]

  1. ND not defined, Missing data treated by random.
  2. *Applying Kruskal Wallis test.
  3. †applying Pearson Chi-Square.
  4. ‡Applying Man-Whitney U-test.
  5. §Comparing ages in three outcomes.
  6. Comparing time of admission post-ingestion.
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