Figure 1 | Scientific Reports

Figure 1

From: Antibody–nanobody combination increases their neutralizing activity against SARS-CoV-2 and nanobody H11-H4 is effective against Alpha, Kappa and Delta variants

Figure 1

(A) Schematic description of the S protein of SARS-CoV-2, which consists of the S1 and S2 subunits. (B) SARS-CoV-2 S protein binds to human ACE2 before entering cells. (C) H11-H4 and CR3022 bind to S protein, preventing the virus from entering cells. The 3D structures of H11-H4 and CR3022 bound to RBD are shown in all-atom (D) and coarse-grained (E) models.

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