Figure 1

(A) QTL mapping curve of the locus on chromosome 1 for liver weight. The black (1%) and grey (5%) horizontal lines mark the significance thresholds; likelihood ratios above the black line are formally highly significant (LOD > 5.1), likelihood ratios above the grey line are formally significant (LOD > 4.4). (B) Boxplots for two genotype classes (BFMI-S1, BFMI861-S1 homozygous; HET, heterozygous) at SNP gUNC2036998 which is located at the top position for liver weight. (C) QTL mapping curve on chromosome 6 for body weight at week 16 after performing MQM. (D) Boxplots for all three genotype classes (BFMI-S1, BFMI861-S1 homozygous; HET, heterozygous; B6N, C57BL/6 N homozygous) at SNP gUNC10595065 which is located at the top position for body weight at week 16 after performing MQM.