Table 1 Summary of patient characteristics and source of DNA.

From: Enrichment of cancer-predisposing germline variants in adult and pediatric patients with acute lymphoblastic leukemia

 

Adults

Children

Number of patients

61

87

Male

40 (66%)

59 (68%)

Female

21 (34%)

28 (32%)

Age at dg (y)

16–70

0–16

Mean age at dg (y)

38

7

ALL type

B-ALL

36 (59%)

66 (76%)

T-ALL

17 (28%)

11 (13%)

Ph-ALL

8 (13%)

10 (11%)

Source of DNA

Skina

Bloodb

  1. Dg, diagnosis; y, years; B-ALL, Ph-negative B-ALL; Ph-ALL, Ph-positive B-ALL.
  2. aOne adult patient’s DNA was extracted from blood, but after recovering from ALL.
  3. bSee methods for determining the germline/somatic origin of variants.
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