Figure 5
From: Smurf2 inhibition enhances chemotherapy and radiation sensitivity in non-small-cell lung cancer

Smurf2 gene expression predicts tumor progression and mortality in patients with stage III squamous NSCLC. Overall survival and disease-free survival were significantly reduced in the high-Smurf2 expression groups of patients with stage III disease treated with chemotherapy (n = 85) (A) or treated with combined radiotherapy and chemotherapy (n = 25) (B). The black and red lines indicate the 1st and 4th quartiles of expression, respectively. See Table 1 for the associated HRs and 95% CIs.