Figure 4 | Scientific Reports

Figure 4

From: RNA modification patterns based on major RNA modifications define tumor microenvironment characteristics in glioblastoma

Figure 4

Generation of the RNA modification regulator model. (A) An unsupervised clustering method was used to classify GBM patients into gene subgroups based on the DEGs of distinct RNA modification patterns. (B) Kaplan–Meier curves for cluster A and cluster B. (C,D) The Wilcoxon test was performed to assess differences in the GBM scores between distinct RNA modification patterns and gene-subgroups. (E) The ssGSEA score of immune cells in high and low GBM score groups. (F) The survival analysis of patients with GBM scores in high and low subgroups. (G) The AUC for the GBM score for patients with 365 days, 1095 days, or 1825 days overall survival. (H) Multivariate Cox regression model analysis in the TCGA-GBM cohorts.

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