Table 3 Effect of oral administration of MA leaves, pseudostem and fruit peels extracts on liver and kidney function tests of rats in subchronic toxicity study.

From: Pharmacological and metabolomic profiles of Musa acuminata wastes as a new potential source of anti-ulcerative colitis agents

Groups

Parameter

ALT (U/L)

AST (U/L)

Urea (mg/dL)

Creatinine (mg/dL)

Negative control

36.08 ± 2.54

27.78 ± 1.14

30.1 ± 1.74

0.95 ± 0.03

MA leaves (250 mg/kg)

34.9 ± 0.38

21.22 ± 0.9

27.52 ± 2.9

0.84 ± 0.05

MA leaves (500 mg/kg)

30.05 ± 0.31

24.32 ± 1.8

24.5 ± 3.84

0.79 ± 0.04

MA pseudostem (250 mg/kg)

40.97 ± 2.29

27.64 ± 2.96

36.49 ± 0.07

0.93 ± 0.03

MA pseudostem (500 mg/kg)

35.43 ± 3.29

22.51 ± 2.33

27.52 ± 0.78

0.71 ± 0.05

MA fruit peels (250 mg/kg)

41.9 ± 1.64

23.17 ± 1.7

33.15 ± 0.54

0.72 ± 0.1

MA fruit peels (500 mg/kg)

27.92 ± 0.72

26.78 ± 2.8

22.14 ± 1.87

0.78 ± 0.02

  1. Results are expressed as means of levels of ALT, AST, urea and creatinine in rat sera ± SE. n = 8; Data were analysed using one way analysis of variance (ANOVA) followed by Tukey Kramer’s multiple comparison test. No significant difference detected among groups.