Table 2 Univariate and multivariate Cox regression analysis of characteristics and Signature RS in CESC.

From: Construction of a four-mRNA prognostic signature with its ceRNA network in CESC

Clinical parameter

N

Univariate analysis

Multivariate analysis

HR (95% CI)

P

HR (95% CI)

P

Age

 

1.79(0.84–3.8)

0.13

 ≤ 65

192

    

 > 65

48

    

M stage

 

3.55(1.2–10.55)

0.02

0 (0–lnf)

1

M0

107

    

M1

10

    

N stage

 

2.6(1.32–5.11)

0.01

1.51(0.56–4.06)

0.42

N0

125

    

N1 + 

53

    

T stage

 

3.58(1.89–6.77)

0.001

3.58(1.89–6.77)

0.16

T1-T2

200

    

T3-T4

26

    

Pathological stage

 

5.77(3.01–11.05)

0.001

1.22(0.17–8.67)

0.84

I–II

125

    

III–IV

53

    

Histological types

 

1.13(0.55–2.31)

0.74

Adenosquam-ous

47

    

Squamous

193

    

Signature RS

 

0.22(0.12–0.41)

1.5e − 6

6.35(1.66–24.3)

0.01

High

120

    

Low

120

    
  1. N number of patients, HR hazard ratio, CI confidence interval, RS risk score, P P value (unadjusted).