Table 2 Univariate and multivariate Cox regression analysis of characteristics and Signature RS in CESC.
From: Construction of a four-mRNA prognostic signature with its ceRNA network in CESC
Clinical parameter | N | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | ||
Age | 1.79(0.84–3.8) | 0.13 | – | – | |
≤ 65 | 192 | ||||
> 65 | 48 | ||||
M stage | 3.55(1.2–10.55) | 0.02 | 0 (0–lnf) | 1 | |
M0 | 107 | ||||
M1 | 10 | ||||
N stage | 2.6(1.32–5.11) | 0.01 | 1.51(0.56–4.06) | 0.42 | |
N0 | 125 | ||||
N1 + | 53 | ||||
T stage | 3.58(1.89–6.77) | 0.001 | 3.58(1.89–6.77) | 0.16 | |
T1-T2 | 200 | ||||
T3-T4 | 26 | ||||
Pathological stage | 5.77(3.01–11.05) | 0.001 | 1.22(0.17–8.67) | 0.84 | |
I–II | 125 | ||||
III–IV | 53 | ||||
Histological types | 1.13(0.55–2.31) | 0.74 | – | – | |
Adenosquam-ous | 47 | ||||
Squamous | 193 | ||||
Signature RS | 0.22(0.12–0.41) | 1.5e − 6 | 6.35(1.66–24.3) | 0.01 | |
High | 120 | ||||
Low | 120 |