Table 2 Summary of Mann–Whitney U tests on alpha diversity indices across ASD and TD groups.

From: Disentangling the relationship of gut microbiota, functional gastrointestinal disorders and autism: a case–control study on prepubertal Chinese boys

Alpha diversity index

Mean ± SD

p

p (adjusted)

Effect size

ASD

TD

Faith’s PD

7.73 (1.65)

8.17 (1.05)

0.020

0.004

0.31

Chao1 Index

79.8 (19.3)

92.6 (20.2)

< 0.001

< 0.001

0.383

 

Mean ± SD

p

p (adjusted)

Effect size

ASD FGID−

TD FGID−

Faith’s PD

7.46 (1.51)

8.12 (1.06)

0.003

< 0.001

0.371

Chao1 Index

79 (19.4)

92.9 (21.3)

< 0.001

< 0.001

0.396

 

Mean ± SD

p

p (adjusted)

Effect size

ASD FGID+

TD FGID+

Faith’s PD

8.27 (1.82)

8.29 (1.03)

0.953

0.496

0.213

Chao1 Index

81.4 (19.4)

91.8 (17.4)

0.030

0.040

0.347

 

Mean ± SD

p

p (adjusted)

Effect size

ASD FGID+

ASD FGID−

Faith’s PD

8.27 (1.82)

7.46 (1.51)

0.027

0.032

0.285

Chao1 Index

81.4 (19.4)

79 (19.4)

0.577

0.487

0.065

 

Mean ± SD

p

p (adjusted)

Effect size

TD FGID+

TD FGID−

Faith’s PD

8.29 (1.03)

8.12 (1.06)

0.451

0.868

0.143

Chao1 Index

91.8 (17.4)

92.9 (21.3)

0.811

0.407

0.02

  1. Significant values are in bold.
  2. ASD: Autism Spectrum Disorder, TD: Typically Developing; Faith’s PD: Faith’s Phylogenetic Diversity. Statistical comparisons were adjusted for usage of psychiatric medications, unhealthy diet, fibre intake and main nutrient intake; Effect sizes were calculated using rank biserial correlation.