Table 5 Comparison of the relative abundance at genus level between ASD and TD groups.

From: Disentangling the relationship of gut microbiota, functional gastrointestinal disorders and autism: a case–control study on prepubertal Chinese boys

General

Mean ± SD

Statistics

ASD FGID−

TD FGID−

p

p FDR

Effect size

Bifidobacterium

18.996 (12.85)

12.072 (9.21)

0.001

0.01

0.317

Bacteroides

13.206 (9.64)

17.085 (10.25)

0.023

0.026

0.223

Blautia

10.432 (5.98)

7.747 (4.07)

0.008

0.016

0.261

Clostridium sensu stricto 1

0.933 (2.19)

1.400 (2.29)

0.046

0.046

0.181

Parabacteroides

0.767 (1.27)

1.291 (1.32)

0.001

0.005

0.313

Alistipes

0.3472 (0.65)

0.958 (1.355)

0.002

0.005

0.29

Collinsella

0.215 (0.59)

0.443 (0.61)

0.002

0.007

0.249

Sutterella

0.075 (0.27)

0.221 (0.49)

0.017

0.028

0.169

Dorea

0.174 (0.54)

0.028 (0.15)

0.021

0.026

0.109

Eggerthellaceae uncultured

0 (0)

0.029 (0.12)

0.018

0.026

0.088

 

Mean ± SD

Statistics

ASD FGID + 

TD FGID + 

p

p FDR

Effect size

Oscillospirales (order)

20.716 (7.53)

18.518 (9.75)

0.036

0.051

0.133

Ruminococcaceae (family)

18.380 (7.24)

15.662 (8.17)

0.037

0.046

0.214

Fusicatenibacter

1.440 (0.88)

0.765 (0.68)

< .001

0.005

0.486

Turicibacter

0.964 (1.35)

0.175 (0.43)

0.001

0.003

0.423

Dialister

0.917 (1.11)

0.345 (0.60)

0.025

0.05

0.303

Phascolarctobacterium

0.124 (0.39)

0.897 (1.09)

< 0.001

< 0.001

0.575

Enterobacter

0.053 (0.18)

0.627 (1.21)

0.033

0.055

0.238

[Eubacterium] eligens group

0.188 (0.54)

0.013 (0.05)

0.024

0.06

0.215

[Eubacterium] ruminantium group

0 (0)

0.124 (0.38)

0.049

0.054

0.125

Weissella

0 (0)

0.013 (0.05)

0.049

0.049

0.125

 

Mean ± SD

Statistics

ASD FGID+

ASD FGID−

p

p FDR

Effect size

Ruminococcaceae (family)

18.380 (7.24)

15.507 (8.66)

0.002

0.02

0.247

Fusicatenibacter

1.440 (0.88)

1.016 (1.00)

0.024

0.048

0.289

Romboutsia

1.6354 (2.92)

0.694 (1.74)

0.03

0.05

0.253

Dialister

0.917 (1.11)

0.474 (0.86)

0.031

0.044

0.252

Turicibacter

0.964 (1.35)

0.269 (0.61)

0.002

0.01

0.351

Collinsella

0.569 (0.77)

0.215 (0.59)

0.003

0.008

0.299

Phascolarctobacterium

0.124 (0.39)

0.450 (0.90)

0.002

0.007

0.339

Christensenellaceae uncultured

0.006 (0.02)

0 (0)

0.043

0.054

0.067

F0332

0.004 (0.01)

0 (0)

0.043

0.048

0.067

Abiotrophia

0.004 (0.02)

0 (0)

0.043

0.043

0.067

  1. Significant values are in bold.
  2. ASD Autism Spectrum Disorder, TD Typically Developing, FGID Functional Gastrointestinal Disorder. P-values corrected for false discovery rate using the Benjamini–Hochberg method. Effect sizes were calculated with rank biserial correlation. Genera are presented in descending order of relative abundance.
Back to article page