Table 4 Effects of baseline incidence, proportions diseased, risk ratios, and baseline symptom correlations on overall symptom correlations.
From: Diagnostic accuracy of symptoms for an underlying disease: a simulation study
Coefficients | (95% CIs) | p | |
|---|---|---|---|
Incidence not reaching 1 among those diseased | |||
(Intercept) | − 0.007 | (− 0.008 to − 0.006) | < 0.0001 |
Correlation between diseases | 0 | (− 0.001 to 0.001) | 0.859 |
Proportions diseased | 0.119 | (0.117 to 0.121) | < 0.0001 |
Baseline incidence | − 0.107 | (− 0.109 to − 0.105) | < 0.0001 |
Risk ratio | 0.016 | (0.016 to 0.016) | < 0.0001 |
At-risk incidence | 0.185 | (0.183 to 0.187) | < 0.0001 |
Baseline symptom correlation | 0.841 | (0.840 to 0.842) | < 0.0001 |
Dependent variables mean = 0.5; SD = 0.31; median = 0.47; min = − 0.04; max = 0.99 | |||
Adjusted R-square = 0.89 | |||
Incidence reaching 1 among those diseased | |||
(Intercept) | 0.339 | (0.336 to 0.342) | < 0.0001 |
Correlation between diseases | 0 | (− 0.002 to 0.002) | 0.736 |
Proportions diseased | 0.315 | (0.312 to 0.318) | < 0.0001 |
Baseline incidence | − 0.337 | (− 0.341 to − 0.333) | < 0.0001 |
Risk ratio | 0.01 | (0.01 to 0.01) | < 0.0001 |
Baseline symptom correlation | 0.639 | (0.637 to 0.641) | < 0.0001 |
Dependent variables mean = 0.62; SD = 0.29; median = 0.72; min = − 0.02; max = 0.99 | |||
Adjusted R-square = 0.86 | |||
