Table 5 Effects of baseline incidence, proportions diseased, risk ratios, and baseline symptom correlations on the sensitivities of individual symptoms for disease diagnosis.

From: Diagnostic accuracy of symptoms for an underlying disease: a simulation study

 

Coefficients

(95% CIs)

p

Incidence not reaching 1 among those diseased

(Intercept)

0

(0 to 0)

< 0.0001

Correlation between diseases

0

(0 to 0)

0.82

Proportions diseased

0

(0 to 0)

0.03

Baseline incidence

0

(0 to 0)

< 0.0001

Risk ratio

0

(0 to 0)

< 0.0001

At-risk incidence

1

(1 to 1)

< 0.0001

Baseline symptom correlation

0

(0 to 0)

0.22

Dependent variable mean = 0.64; SD = 0.32; median = 0.55; min = 0.12; max = 1

Adjusted R-square = 1

Incidence reaching 1 among those diseased

(Intercept)

1

(1 to 1)

< 0.0001

Correlation between diseases

0

(0 to 0)

0.24

Proportions diseased

0

(0 to 0)

0.34

Baseline incidence

0

(0 to 0)

0.22

Risk ratio

0

(0 to 0)

0.71

Baseline symptom correlation

0

(0 to 0)

0.22

Dependent variable mean = 1; SD = 0; median = 1; min = 1; max = 1

Adjusted R-square = 0.5

  1. CI confidence interval, SD standard deviation.