Table 6 Effects of baseline incidence, proportions diseased, risk ratios, and baseline symptom correlations on the specificities of individual symptoms for disease diagnosis.

From: Diagnostic accuracy of symptoms for an underlying disease: a simulation study

 

Coefficients

(95% CIs)

p

Incidence not reaching 1 among those diseased

(Intercept)

1

(1 to 1)

< 0.0001

Correlation between diseases

0

(0 to 0)

0.03

Proportions diseased

0

(0 to 0)

0.01

Baseline incidence

− 1

(− 1 to − 1)

< 0.0001

Risk ratio

0

(0 to 0)

< 0.0001

At-risk incidence

0

(0 to 0)

< 0.0001

Baseline symptom correlation

0

(0 to 0)

0.1

Dependent variable mean = 0.62; SD = 0.27; median = 0.61; min = 0.17; max = 0.97

Adjusted R-square = 1

Incidence reaching 1 among those diseased

(Intercept)

1

(1 to 1)

< 0.0001

Correlation between diseases

0

(0 to 0)

0.95

Proportions diseased

0

(0 to 0)

0.24

Baseline incidence

− 1

(− 1 to − 1)

< 0.0001

Risk ratio

0

(0 to 0)

< 0.0001

Baseline symptom correlation

0

(0 to 0)

0.97

Dependent variable mean = 0.61; SD = 0.29; median = 0.63; min = 0.17; max = 0.97

Adjusted R-square = 1

  1. CI confidence interval, SD standard deviation.