Table 6 Effects of baseline incidence, proportions diseased, risk ratios, and baseline symptom correlations on the specificities of individual symptoms for disease diagnosis.
From: Diagnostic accuracy of symptoms for an underlying disease: a simulation study
Coefficients | (95% CIs) | p | |
---|---|---|---|
Incidence not reaching 1 among those diseased | |||
(Intercept) | 1 | (1 to 1) | < 0.0001 |
Correlation between diseases | 0 | (0 to 0) | 0.03 |
Proportions diseased | 0 | (0 to 0) | 0.01 |
Baseline incidence | − 1 | (− 1 to − 1) | < 0.0001 |
Risk ratio | 0 | (0 to 0) | < 0.0001 |
At-risk incidence | 0 | (0 to 0) | < 0.0001 |
Baseline symptom correlation | 0 | (0 to 0) | 0.1 |
Dependent variable mean = 0.62; SD = 0.27; median = 0.61; min = 0.17; max = 0.97 | |||
Adjusted R-square = 1 | |||
Incidence reaching 1 among those diseased | |||
(Intercept) | 1 | (1 to 1) | < 0.0001 |
Correlation between diseases | 0 | (0 to 0) | 0.95 |
Proportions diseased | 0 | (0 to 0) | 0.24 |
Baseline incidence | − 1 | (− 1 to − 1) | < 0.0001 |
Risk ratio | 0 | (0 to 0) | < 0.0001 |
Baseline symptom correlation | 0 | (0 to 0) | 0.97 |
Dependent variable mean = 0.61; SD = 0.29; median = 0.63; min = 0.17; max = 0.97 | |||
Adjusted R-square = 1 |