Table 7 Effects of baseline incidence, proportions diseased, risk ratios, and baseline symptom correlations on the area under the receiver operating characteristic curve of individual symptoms for disease diagnosis.
From: Diagnostic accuracy of symptoms for an underlying disease: a simulation study
Coefficients | (95% CIs) | p | |
|---|---|---|---|
Incidence not reaching 1 among those diseased | |||
(Intercept) | 0.5 | (0.5 to 0.5) | < 0.0001 |
Correlation between diseases | 0 | (0 to 0) | 0.25 |
Proportions diseased | 0 | (0 to 0) | 0.57 |
Baseline incidence | − 0.5 | (− 0.5 to − 0.5) | < 0.0001 |
Risk ratio | 0 | (0 to 0) | < 0.0001 |
At-risk incidence | 0.5 | (0.5 to 0.5) | < 0.0001 |
Baseline symptom correlation | 0 | (0 to 0) | 0.44 |
Dependent variable mean = 0.63; SD = 0.27; median = 0.6; min = 0.27; max = 0.98 | |||
Adjusted R-square = 1 | |||
Incidence reaching 1 among those diseased | |||
(Intercept) | 1 | (1 to 1) | < 0.0001 |
Correlation between diseases | 0 | (0 to 0) | 0.21 |
Proportions diseased | 0 | (0 to 0) | 0.37 |
Baseline incidence | − 0.5 | (− 0.5 to − 0.5) | < 0.0001 |
Risk ratio | 0 | (0 to 0) | < 0.0001 |
Baseline symptom correlation | 0 | (0 to 0) | 0.06 |
Dependent variable mean = 0.8; SD = 0.15; median = 0.8; min = 0.59; max = 0.98 | |||
Adjusted R-square = 1 | |||
