Table 1 Comparisons of baseline characteristics and outcomes between survivors and nonsurvivors in patients with severe sepsis and septic shock.
Survivors (N = 137) | Non-survivors (N = 69) | p-value | |
|---|---|---|---|
Demographic characteristics | |||
Age, median (IQR), year | 65 (29) | 61 (31) | 0.607 |
Female, n (%) | 48 (35) | 22 (31.9) | 0.768 |
Comorbidities, n (%) | |||
Chronic heart failure | 13 (9.5) | 19 (27.5) | 0.002 |
Diabetes mellitus | 31 (22.6) | 15 (21.7) | 1.000 |
Cerebrovascular disease | 27 (19.7) | 19 (27.5) | 0.273 |
Chronic kidney disease | 19 (13.9) | 23 (33.3) | 0.002 |
Laboratory results, median (IQR) | |||
White blood cell count (109/L) | 11.0 (7.06) | 12.0 (9.49) | 0.729 |
Neutrophil percentage (%) | 86.0 (11.5) | 87.7 (11.9) | 0.504 |
Procalcitonin(ng/dL) | 0.65 (5.86) | 7.06 (27.70) | < 0.001 |
Lactate (mmol/L) | 1.8 (1.7) | 3.5 (5.1) | < 0.001 |
Site of infection, n (%) | |||
Bloodstream | 2 (1.5) | 9 (13.0) | 0.002 |
Lung | 112 (81.8) | 68 (98.6) | 0.001 |
Urinary tract | 9 (6.6) | 2 (2.9) | 0.437 |
Abdomen | 18 (13.1) | 15 (21.7) | 0.165 |
Soft tissue | 2 (1.5) | 1 (1.4) | 1.000 |
Others | 4 (2.9) | 1 (1.4) | 0.867 |
Clinical scoring, points, median (IQR) | |||
APACHE II score | 14 (9) | 25 (8) | < 0.001 |
SOFA score | 5 (6) | 13 (8) | < 0.001 |
Charlson score | 2 (3) | 4 (3) | < 0.001 |
Number dysfunctional organs | 2(1) | 4(2) | < 0.001 |
Organ support, n (%) | |||
Mechanical ventilation | 21 (15.3) | 30 (43.5) | < 0.001 |
Renal replacement therapy | 6 ( 4.4) | 28 (40.6) | < 0.001 |
Vasopressor | 36 (26.3) | 53 (76.8) | < 0.001 |
Duration of hospitalization, mean ± SD, days | |||
Length of ICU stay, median (IQR) | 6 (8) | 4 (12) | < 0.001 |
Length of hospital stay, median (IQR) | 14 (14) | 5 (12) | < 0.001 |
